Neoadjuvant botensilimab plus balstilimab response pattern in locally advanced mismatch repair proficient colorectal cancer
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Oncogene
September 21, 2023
,
Colorectal (CRC)
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Botensilimab (Fc-enhanced anti-CTLA-4)
Balstilimab (PD-1 inhibitor)
Results from an expanded phase 1 trial of botensilimab, a multifunctional anti-CTLA-4, plus balstilimab(anti-PD-1) for metastatic heavily pretreated microsatellite stable colorectal cancer
ESMO
European Society for Medical Oncology, Gastrointestinal (ESMO- GI)
June 28, 2023
,
Bullock, et al.
Colorectal (CRC)
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Phosphopeptide Targets
Molecular mechanism of phosphopeptide neoantigen immunogenicity
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Nature Communications
June 23, 2023
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AGEN2373 (CD137 Agonist)
A Phase 1 Study of AGEN2373, a Novel CD137 Agonist Antibody Designed to Avoid Hepatoxicity, in Patients with Advanced Solid Tumors