Publications

Publishing the Frontiers of Immuno-Oncology

Spotlight Publication

Botensilimab (Fc-enhanced anti-CTLA-4), Balstilimab (PD-1 inhibitor)

Emerging survival plateaus with botensilimab and balstilimab: Pan tumor data from a large phase 1b trial of advanced solid tumors

Oct 17, 2025
,
Gordon et al.
ESMO
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Clinical Trials
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Botensilimab (Fc-enhanced anti-CTLA-4)
Balstilimab (PD-1 inhibitor)

Results from a phase 1a/1b study of botensilimab (BOT), a novel innate/adaptive immune activator, plus balstilimab (BAL; anti-PD-1 antibody) in metastatic heavily pretreated microsatellite stable colorectal cancer (MSS CRC)

ASCO
American Society of Clinical Oncology, Gastrointestinal (ASCO-GI)
January 23, 2023
,
El-Khoueiry, et al.
Balstilimab (PD-1 inhibitor)
Botensilimab (Fc-enhanced anti-CTLA-4)

A Phase IA/IB study of Botensilimab, a novel innate/adaptive immune activator, plus Balstilimab for the treatment of patients with sarcoma

CTOS
Connective Tissue Oncology Society (CTOS)
November 18, 2022
,
Wilky, et al.
Balstilimab (PD-1 inhibitor)
Botensilimab (Fc-enhanced anti-CTLA-4)

Botensilimab, a novel innate/adaptive immune activator with balstilimab (anti-PD-1) in “cold” and I-O refractory metastatic solid tumors

SITC
Society for Immunotherapy of Cancer (SITC)
November 14, 2022
,
Wilky, et al.
No items found.
Botensilimab (Fc-enhanced anti-CTLA-4)

Botensilimab, a novel Fc-enhanced anti-CTLA-4 antibody enhances T cell: APC functionality and promotes superior anti-tumor immunity

SITC
Society for Immunotherapy of Cancer (SITC)
November 14, 2022
,
Levey, et al.
No items found.
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