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Marwan G. Fakih, MD, discussed the implications of the findings from the phase 2 study for patients with microsatellite stable metastatic colorectal cancer without liver metastases.
Neoadjuvant botensilimab and balstilimab showed high MPR rates in MSS and MSI-H CRC, with no recurrences reported.
The major pathologic response rate improved with extended time to surgery using botensilimab plus balstilimab in resectable colorectal cancer.
An immunotherapy combination for advanced, highly mutated colorectal cancer (CRC) significantly slowed disease progression versus a single drug, according to a randomized study.
Balstilimab and botensilimab combination therapy showed superior efficacy in MSS mCRC patients without liver metastases compared to botensilimab monotherapy.