Careers

We are dedicated scientists, researchers, biotechnologists, physicians, and businesspeople working together toward one goal: minimize the burden of cancers and infections by helping the body heal itself through the power of science.

The work we do at Agenus is cutting edge and deeply motivating. We believe passionately in our technology, in our pipeline, and in our responsibility to deliver on the promise of immunology to treat cancer and infectious disease. If you’re looking for an inspired environment, passionate colleagues, and a culture that nurtures learning, innovation and team success, we invite you to join us.

To learn more about current openings, please contact our Human Resources department.

Current Openings

Jena, Germany

Lexington, MA

Director of Facilities & Engineering (886)

Description:

Agenus is looking for a Director of Facilities and Engineering. The successful candidate will be responsible for the strategic management of Agenus’ global real estate and workplace, and proactively manage our facility operations. In addition to keeping our facilities up-to-date and in compliance with our programs and policies, the successful candidate will develop new best practices and innovations and develop a strategy for lab & office space, global needs and space planning initiatives.

Primary Accountabilities

  • Ensure all utilities, equipment and general building systems are maintained in compliance with all relevant safety, environmental security, cGMP requirements, and corporate standards by ensuring preventive and corrective maintenance is executed in timely manner.
  • Responsible to oversee personnel including contractors, consultants and temporary employees have the necessary qualifications and training to perform their job in accordance to regulations.
  • Maintain all facilities and properties state of cleanliness as required by GMP and Non-GMP.
  • Work with the Quality Group to ensure environmental facilities are maintained to regulations as well as local, state, federal, and international laws and regulations
  • Responsible for office workplace and lab space strategy
  • Serve as a strategic advisor to the business by delivering required facilities related services that consistently benchmark under market cost
  • Collaborate with cross-functional organizations like IT and human resources to streamline processes and increase efficiencies while maintaining a high level of customer service
  • Manage global engineering programs and response SLAs supporting highly technical lab facilities and other critical environments
  • Manage and support a high-performing global team, building solid relationships with our associates while managing a "best in class" facilities portfolio
  • Ensure operational efficiency and performance standards are met through auditing and documentation of maintenance, monitoring, and inspection of all building infrastructure systems and services
  • Develop facilities operating and capitalized budgets for assigned portfolio; plan ahead, track variances, and manage funds wisely

Experience and education needed:

  • 10+ years of experience in a global manufacturing or commercial facility leadership role
  • Experience with large construction, engineering and architectural projects preferred
  • Working knowledge of building utility and life safety systems, maintenance best practices and Pharmaceutical/Biologics manufacturing
  • Working knowledge of cGMPs requirements within a regulated environment
  • Excellent written and verbal communication skills, and an ability to collaborate with different backgrounds and cultures
  • Willingness to travel up to 30%

Bachelor’s degree in Engineering, i.e. Mechanical, Chemical or Electrical Certified Facility Manager (CFM), Certified Healthcare Facilities Manager (CHFM), Certified Professional Maintenance Manager (CPMM), Certified Plant Engineer (CPE) or equivalent preferred.

Junior Paralegal (884)

Description:

Contract Administration responsibilities include: (i) managing contract database (accurately enter data and contracts), (ii) ensuring contract execution is in accordance with established legal department and company policies and procedures, and (iii) assisting with drafting/initiating routine correspondence and agreements (i.e. confidentiality agreements, consulting agreements, services agreements and amendments). Corporate Governance responsibilities include: (i) assisting with production and dissemination of materials for meetings of the Board of Directors, (ii) assisting with corporate governance related filings, and (iii) assisting with drafting Board and Committee meeting minutes. Perform miscellaneous tasks and other duties for effective implementation, management, and upkeep of company contracts, corporate records, and legal and intellectual property department and compliance administration as requested.

Experience and Education needed:

Comments Agenus is seeking a paralegal with 1-3 years of experience working in a law firm or corporate setting (biotech or pharma experience preferred) to join and support the needs of a growing in-house counsel team in the areas of Contract Administration, Corporate Governance, and Intellectual Property. The successful candidate has superior attention to detail, excellent writing skills, the ability to efficiently multi-task, strong proficiency in Microsoft Office, excellent proofreading abilities, strong organizational and communication skills, and the ability to work in a fast-paced environment, meet deadlines, prioritize time-sensitive tasks, and work across organizational and geographic boundaries.

BA/BS and Paralegal certificate required. Notary Public a plus. Prior experience with intellectual property and/or scientific acumen a plus.

Desktop Support Specialist (887)

Description:

The Desktop Support Specialist is primarily responsible for ensuring continuity of IT services for users by providing the technical expertise, assistance and project coordination necessary to deploy, configure and support computer hardware/software products including peripherals, desk/mobile phones and desktop/conference room based audio/video. The right candidate will be someone who has strong interpersonal skills, along with excellent communication and listening skills. The Desktop Support Specialist must be flexible, well organized and pay close attention to detail. Provide front line helpdesk support Deploy, upgrade and configure PCs/Macs/tablets/printers/desk phones/smartphones and other end user related computer/networking peripherals. End user application installation, support, training centered around the office suite, other productivity applications and various scientific software packages Work closely with other IT staff and outside vendors to ensure continuity and a high level of service. Provide technical assistance and advice to users as needed. Support audio/video systems used on desktop and in the conference rooms throughout the company offices Help to ensure users are aware of, trained on and adhering to company policies and SOPs. Assist with the modification and development of documentation to support the IT function Assist in implementing practices that will more effectively utilize IT resources. Must be “on-call” for all periods as assigned by manager. Stay abreast of the latest developments in IT. Other responsibilities and projects may be assigned as needed.

Experience and Education needed:

Hardware: desktops, laptops, printers, tablets, desk phones, smartphones, other computer peripherals, network switches Operating Systems: Windows XP/7/8/10, OSX, Windows 2012 MS Office Suite 2010 and above, MS Visio, MS Project, Office 365, Adobe Creative Suite, Desktop conferencing (WebEx, Skype, Zoom, etc…), various scientific applications Active Directory, Microsoft Exchange, SharePoint A/V: projectors, LED displays, Polycom tabletop conference phones, Logitech webcam, Polycom video codecs, audio conference bridge services, conference room automation Digital and IP based enterprise phone systems Basic networking (switching, VLANs) Support of various instrument based and non-instrument based scientific/research software

BA or AA Degree in Computer Science

Scientist, Cell Line Development (814)

Description:

This position will be responsible for cell culture and upstream process development for multiple monoclonal antibody products intended for preclinical and Phase I clinical studies. Responsibilities will include development of high performance cell culture process from stable pool or selected research cell bank (RCB) of engineered CHO cells in shake flasks and bench-top bioreactors; generation of high titer monoclonal antibodies secreted culture media harvest; purification of multi-gram quantity of mAb for preclinical studies and reference materials; participation in preclinical to Phase I process and product comparability studies; support of CMC process control with project teams and CMO’s.

Experience and Education needed:

  • Experiences in cell culture process scale up, scale down, characterization and transfer are required;
  • Demonstrated success in technical proficiency, bioreactor operation, timely delivery of multi-gram quantity of mAb for preclinical studies and reference material use;
  • Understanding data acquisition and process control, and data management is also required, experience in a cGMP production environment is a plus;
  • Other requirements include knowledge and experience in statistics and DOE, interpersonal and organizational skills, oral and written communication skills, ability of multi-tasking effectively and operate both independently and in team settings
  • PhD with a minimum of 5 years of experience developing mammalian cell culture process development for protein preferably monoclonal antibody expression experience

Patent Attorney (867)

Description:

We are seeking a highly qualified Patent Attorney with a technical background and advanced degree in the life sciences, ideally with an immunology focus. Experience in due diligence analyses (including freedom-to-operate and related analyses) is required. The qualified individual will be a key contributor to assisting the company in evaluating and supporting development of new technologies. The qualified individual will also work closely with the corporate legal department in reviewing agreements with intellectual property provisions. Registration to practice before the United States Patent and Trademark Office along with an admission to a state bar is required. Excellent academics and strong written and oral communication skills are necessary, as this position will interface regularly with scientists and management.

Experience and Education needed:

  • 3-7 years of experience in IP due diligence analyses and related work in the biologics space in a law firm or corporate setting
  • Registration to practice before the United States Patent and Trademark Office along with admission to a state bar
  • Experience with contract review is highly preferred
  • Knowledge of antibody drug development is a plus
  • Experience with contested proceedings (e.g., litigation, oppositions, IPRs) is a plus
  • Must have solid organizational skills and ability to think strategically and systematically, analyze complex business issues, and utilize sound judgment in deriving conclusions
  • Demonstrated ability to achieve results
  • Strong interpersonal skills and ability to work in a highly collaborative environment
  • Excellent academics
  • Strong written and oral communication skills
  • Advanced degree (PhD preferred) in immunology or related life-sciences discipline

Senior Bioinformatics Scientist (862)

Description:

Analyze and interpret high-throughput internal DNA and RNA sequencing data from Illumina sequencing platforms, with a specific focus on mutation identification and immunological characterization

Experience and Education needed:

  • Analyze and interpret external molecular ‘big data’ profiling data, including cancer mutation, gene expression, and immunological data
  • Tight interactions with biotechnology and immunology teams
  • Apply findings in both R&D and clinical projects for biomarkers and immunotherapies
  • Demonstrated excellence processing and analyzing large NGS datasets
  • Extensive experience developing new software tools
  • Proven statistical skills for data mining
  • Excellent data visualization and communication skills
  • Self-starter who works effectively in an agile start-up environment
  • Enthusiastic team player Preferred
  • Experience with cancer and immunologic pathways
  • Familiarity with computational immunology, such as T cell signaling pathways and TCR-peptide-MHC interactions
  • Familiarity with bio-lead structures, including BCRs and TCRs
  • PhD with extensive experience in bioinformatics, biostatistics, or related field

Scientist - PhD Protein Biochemist (855)

Description:

The company is seeking a PhD-level protein biochemist with two to ten years of post-doctoral experience to join our research biochemistry group in Lexington, MA. This is a hands-on laboratory leadership position. Preferred candidates will have extensive experience in the isolation and characterization of proteins and the development of assays for the interactions of proteins with their binding partners, and will be broadly knowledgeable and experienced in the use of molecular biology and biophysical methods. Experience in drug screening, characterization and/or pharmacology is desirable. Candidates should be broadly knowledgeable in the use of various kinds of laboratory instrumentation and automation as well in the use of computers and software as they apply to drug discovery and development. They should also be conversant in peptide chemistry, immunology, pharmacology, and structural biology. Excellent interpersonal and communication skills are essential.

Experience necessary:

2-10 years post PhD experience, preferably including academic postdoctoral experience or broad industrial experience. See also above Job Duties section for additional details on specific skill and experience requirements

Education:

PhD in Biochemistry, Protein Chemistry or Molecular Biology. Undergraduate degree in chemistry or biology. Post-doc experience can be in a different field if relevant to overall capabilities.

Scientist - PhD Peptide Chemist (853)

Description:

Agenus is seeking a PhD-level organic chemist with two to ten years of post-doctoral experience to join our research biochemistry group in Lexington, MA. This is a hands-on laboratory leadership position. Preferred candidates will have extensive experience in high-throughput peptide synthesis and characterization and must be broadly knowledgeable in synthetic methods for standard and modified peptide synthesis. Experience achieving synthesis of “difficult” sequences is a plus as is experience with regulations related to cGMP processes and regulatory filings. Experience in drug screening, characterization and/or pharmacology is desirable. Candidates should be broadly knowledgeable in the use of various kinds of laboratory instrumentation (especially various modes of chromatography and mass spectrometry) and automation as well in the use of computers and software as they apply to drug discovery and development. They should also be conversant in protein biochemistry, immunology, pharmacology, and structural biology. Excellent interpersonal and communication skills are essential.

Experience necessary:

2-10 years post PhD experience, preferably including academic postdoctoral experience or broad industrial experience. See also above Job Duties section for additional details on specific skill and experience requirements

Education:

  • PhD in organic chemistry or biochemistry
  • BS/MS in chemistry or biochemistry
  • Post-doc experience can be in a different field if relevant to overall capabilities

Development Team Leader (864)

Description:

  • Creating and executing a clear, integrated clinical development strategy for immunotherapy that will ultimately lead to regulatory approvals
  • Identifying, developing and implementing immuno-oncology asset and immuno-oncology combination regimens that have a strong mechanistic rationale, the potential to substantially improve upon the current standard of care, and support an aggressive clinical development plan
  • Leading collaborations with world experts (including other companies where appropriate) in the field of immuno-oncology to ensure optimization of the immunotherapy strategy and pipeline
  • Responsible for coordinating a cross functional Team(s) comprised of colleagues from Clinical Development, Medical Affairs, Translational Oncology, Statistics, Clinical Pharmacology, Regulatory, Safety, Project Management, Operations, Commercial Development, and Finance and other functions as determined by the needs of the team
  • Coordinate with the Translational Oncology Lead on the Asset Team in the thoughtful integration of biomarker and companion diagnostic studies into the clinical development strategy for each asset
  • Ensures that the project is managed appropriately per budget
  • Accountable for ensuring that the necessary resources are applied to the project team to support its success
  • Promotes a culture of innovation within the cross-functional team(s) in order to bring forward creative development plans that maximize the potential of each asset
  • May act as point of contact and project representative to governance and other decision-making bodies, including information dissemination and the resolution of critical project issues
  • Leverages line expertise to achieve the team goals
  • Able to engage with Business Development and contribute to efforts to optimize pre and post-PoC immuno oncology portfolio though in-licensing, out-licensing, co-sponsorship, and other collaborative efforts
  • Creates a motivated, committed and engaged project team
  • Models and expects effective team behavior to achieve the project goals
  • Manages key interdivisional interfaces on project issues including but not limited to research, regulatory affairs, development, commercial, medical affairs, manufacturing and operations.

Education and other necessary skills:

  • MD Training Preferred: Proven ability to function effectively across a complex matrix organization with multiple stakeholders and constituents Minimum of 5 years of relevant experience in the pharmaceutical, academic and/or medical research environments having successfully executed a major component of a development program.
  • Significant Phase 1-3 clinical research experience with strong understanding of the elements of drug development programs and experience in their design and execution
  • An organized, independent, self-motivated individual with exceptional presentation, written, and oral communication skills Able to tailor presentations to the knowledge level of the audience to suit their needs and maximize understanding of the topic

Executive Assistant, Finance & Investor Relations (850)

Description:

  • Manage calendars; schedules meetings, makes travel arrangements when needed, manage expense reports for Executive and others
  • Accountable for meeting planning and organization (schedule attendees, books conference rooms, arranges for catering, prepares presentations, compiles notebooks, meeting materials, handouts, etc.)
  • Provides phone support; assumes responsibility for copying, faxing etc.
  • Creates and distributes general correspondence, letters, memos, charts, graphs, contracts, agreements, minutes, spreadsheets reports, and assists in presentation building
  • Proactively responds to questions, concerns, and requests for information and resolves routine questions and information requests
  • Manages the administrative priorities of senior executives, solves conflicting priorities
  • Ad hoc projects, as assigned, including involvement in Board meetings
  • Works on complex problems in which analysis of situations or data requires an in-depth evaluation of various factors
  • Exercises judgment within broadly defined practices and policies in selecting methods, techniques and evaluation criteria for obtaining results

Education and other necessary skills:

  • Must have bachelor’s degree; scientific discipline preferred
  • Must have strong scientific acumen
  • Must have experience supporting senior level management in R&D; 5+ years preferred
  • Extensive and advanced working knowledge of MS Outlook, Word, Excel & PowerPoint
  • Strong interpersonal skills; position continually requires demonstrated poise, tact, and diplomacy
  • Must be able to interact and communicate effectively with individuals at all levels of the organization up to and including Board level
  • Confident, self-starter who can work well with minimum supervision
  • Requires strong attention to detail in composing and proofing materials, establishing priorities, scheduling and meeting deadlines
  • Must be able to work in a fast paced environment with demonstrated ability to simultaneously manage multiple competing tasks and demands
  • Must be flexible in handling multiple tasks of a different nature and have the ability to prioritize efficiently
  • Problem solver who is quick to figure solutions and make things happen
  • Must be able to handle confidential information and issues effectively and without breach of confidentiality

Project Manager - Early Development (840)

Description:

Agenus is devoted to deliver high quality innovative medicines for patients with cancer. We are focused on immuno-oncology and driven to discover, develop and commercialize effective immunotherapeutics and collaborate with partners and leading institutions to realize the full potential of cutting-edge cancer immunotherapies.

We are seeking a highly motivated and strategic Project Manager of Early Phase Development to support the advancement of our checkpoint antibody candidates to IND. We are looking for an industry-experienced PM with the ability to facilitate local and cross-functional activities, apply procedural solutions to operations, and execute on project related decisions.

Responsibilities include:

  • Drive CPM development candidates from lead development candidates through IND enabling programs to early phase programs and identify optimal resource allocation of development project resources
  • Provide accurate, traceable, up-to-date and consistent data as basis decision-making and planning, and transparency on portfolio risks, inter-dependencies, inconsistencies and need for alignment
  • Consult on harmonization of data sources, standardization of study designs, development project management and financial reporting tools
  • Engage multi-disciplinary and cross-functional project teams to constantly improve the ability of the organization to deliver on development commitments
  • Manage key stakeholders to increase alignment to strategic priorities
  • Ensure consistent communication of portfolio decisions and compliance to them, and ensure transparency on technology and product road-maps and their alignment with RPD strategy

Education/Experience:

  • MS/PhD preferred
  • 3-5 years of professional experience, including project management, strategy development, budget development, and vendor management
  • Advanced degree in life sciences (MSc/PhD preferred) or related technical discipline paired with a practical business background
  • Knowledge of antibody-drug development
  • Solid organization and project management skills, ability to think strategically and systematically, analyze complex business issues and opportunities, and utilize sound judgment in deriving conclusions to establish the appropriate objectives and direction
  • Strong interpersonal skills to successfully perform in a complex global matrix environment, excellent stakeholder management skills, proven track record of consensus building and conflict management in challenging situations
  • Strong leadership skills in cross-functional teams with and without direct reporting lines; demonstrated ability to achieve results
  • Experience in multiple external partnerships in early development and good understanding of research and laboratory operations
  • Proven ability to manage multiple simultaneous projects
  • Broad knowledge of research and biological testing, principles, concepts, methods, best practices
  • Broad knowledge of pre-clinical in-vitro assays
  • Extremely strong interpersonal skills, demonstrated ability to work in a highly collaborative environment and ability to achieve results through other managers and people
  • Extremely strong written and oral communication and presentation skills

Sr Research Associate (863)

Description:

Seeking a highly motivated Senior Research Associate to join a group of researchers evaluating novel therapies in the field of cancer immunotherapy. The candidate will explore mechanism of action, combinatorial therapeutic strategies, and elucidate biomarkers to support the identification of companion diagnostics that are predictive of therapeutic response. The successful candidate will work closely with discovery scientists to advance research stage programs into early clinical development, providing both scientific and technical expertise.

Key qualifications:

The position requires a minimum of 8 years of hands-on relevant experience with a track record of success as evidenced by a strong publication record and/or sustained contributions in the biopharmaceutical industry. The candidate should have expertise on a wide range of cellular and biochemical assays, including cell isolation and culture, molecular biology, flow cytometry, cellular immunology assays and some familiarity with in vivo models of immune disease or oncology. Excellent communication skills to present results at intra- and inter-departmental meetings are expected. Experience in multi-dimensional flow cyotmetric analysis is desirable. Qualified candidates should be adept at independently designing, executing and interpreting experiments.

Minimum MS degree in immunology, oncology, biology or related field and a PhD is strongly preferred.

Research Associate

Description:

We are seeking a highly motivated Research Associate to join the Cancer Immunology (T cell Biology) group at Agenus, Lexington, MA. The successful candidate will have a strong background in immunology, molecular immunology and/or oncology research, as evidenced by previous graduate work and co-authorship on peer reviewed publications. He/She will work as part of a dynamic and collaborative global research team to identify and develop novel antibody-based cancer immunotherapies. The successful candidate is expected to have proficiency in a range of immunological techniques including; multi-parameter flow cytometry, primary immune cell cultures and functional assay development; which is complemented by their experience in general molecular/biochemical methodologies. He/she is expected to design, plan and execute experiments both independently and as part of multidisciplinary team of researchers. The successful candidate will have the ability to interpret results, troubleshoot technical hurdles and propose solutions to the team. Excellent written and oral communication skills are required for this position, and he/she is expected to provide clear/concise data summaries in a variety of project team forums. He/she will be also expected to contribute to the preparation of technical documents (example: SOP/ROP), project report summaries, laboratory protocols and other compliance documents.

Responsibilities include:

Key qualifications:

We are seeking an individual who is enthusiastic, self-motivated and has exceptional problem solving and communication skills. A BS/MS degree in biochemistry, molecular biology or related cancer immunology field is required; a MS degree is highly preferred. A minimum of 2-3 yrs experience with primary immune cell assays, general molecular/biochemical techniques and flow cytometry is required for this position. Evidence of an understanding in the principles and techniques employed to characterize antibody-based cancer therapies is highly preferred. He/She should enjoy working independently on project tasks, as well as on more collaborative experiments. Attention to detail, and the ability to maintain clear and accurate research documentation are required, as well as experience with Microsoft Office (and/or other analysis software packages)

A BS/MS degree in biochemistry, molecular biology or related cancer immunology field is required; a MS degree is highly preferred.