Careers

We are dedicated scientists, researchers, biotechnologists, physicians, and businesspeople working together toward one goal: minimize the burden of cancers and infections by helping the body heal itself through the power of science.

The work we do at Agenus is cutting edge and deeply motivating. We believe passionately in our technology, in our pipeline, and in our responsibility to deliver on the promise of immunology to treat cancer and infectious disease. We take great pride in being problem-solvers, trusted partners, opportunity seekers, agile navigators and team players. If you’re looking for an inspired environment, passionate colleagues, and a culture that nurtures learning, innovation and team success, we invite you to join us.

To learn more about current openings, please contact our Human Resources department.

Current Openings

Jena, Germany

Basel, Switzerland

Research Technician: Antibody Discovery

You will be using Retrocyte Display®, our advanced in vitro mammalian display technology, for design and development of cellular fully human antibody libraries as well as for the identification and optimization of fully human antibodies. You will be responsible for the documentation, analysis and interpretation of experiments and you will present your results within a multidisciplinary team environment. Last but not least we will count on your willingness and motivation to tackle both new as well as routine tasks.

Required Qualifications

You hold a B.Sc. or M.Sc. degree in Biology or are a trained lab technician (please note that this position is not suitable for PhDs). You have several years of proven experience in cell biology, biotechnology or immunology. Hands on experience with flow cytometry and in depth knowledge of mammalian cell culture is a must. Molecular biology skills will be an advantage. We are looking for team-oriented candidates who are used to work in an independent and efficient way, are well organized, self-motivated and ready to take on responsibility for their own work as well as for the team. We expect excellent communication skills as well as drive and openness to grow in this position personally and professionally. Fluency in English as well as good working knowledge of standard MS Office software are mandatory requirement.

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Lexington, MA

Sr. Director of Investor Relations and Corporate Communications

Description:

We are seeking a highly motivated individual for the role of Director of Investor Relations and Corporate Communications. This individual will report to the CFO and work closely with the CEO to direct Agenus’ IR strategies and corporate messaging, with oversight of public and media relations.

  • Develop and manage company’s strategic communications
  • Direct the creation and dissemination of external communications pertaining to all major company initiatives, events, and announcements, while providing counsel and feedback to the management team on all such communications. This includes the coordination and oversight of all external communications relating to government, community affairs and patient advocacy
  • Support senior management’s preparedness for calls, conferences and other interactions with the investment community, and direct the implementation of logistics for all such events
  • Create and disseminate the publications and electronic media used in the IR program, including quarterly results and other news releases and periodic updates. Assist with content creation, and direct the production and dissemination of Agenus annual reports
  • Develop and maintain a database of investor relations activities, including a log of senior management meetings and calls with the financial community
  • Oversee company website and related content to ensure regulatory compliance and consistency with corporate image and strategic messaging, and update content in timely fashion to reflect material company events and announcements
  • Analyze shareholder base of Agenus and comparable companies for trends and ownership profiles in order to target appropriate new investors, and to identify divergences in respective shareholder bases
  • Provide competitive intelligence from Wall Street to Agenus management, and collaborate with the Competitive Intelligence staff
  • Manage development of briefing materials for all media relations opportunities, while ensuring regulatory compliance; and coordinate activities with any external media relations vendors
  • Oversee the company’s social media activities to ensure regulatory compliance and consistency with corporate communications objectives
  • Manage internal review processes with subject matter experts

Qualifications and Other Required Knowledge and Skills:

  • 3-5 years’ experience directing Investor relations and corporate communications for a publically traded biotechnology company and a record of accomplishment
  • Exceptional writing skills, including familiarity with common financial and technical jargon, and an ability to distill key business concepts into compelling corporate communications
  • Strong project management skills, and proven experience with planning and oversight of logistics for IR calls, meetings and conferences
  • Ability to function at a high level under pressure, and to thrive in a fast-paced, dynamic environment while managing multiple projects and deadlines simultaneously
  • Strong interpersonal skills with the ability to build and sustain collaborative relationships while managing cross-functional communications and cooperation
  • Advanced degree in a related field, or in the physical sciences, is highly preferred

Research Associate

Description:

This position will participate in the development of analytical methods to support the CMC characterization and comparability studies of preclinical to clinical monoclonal antibody drug substance and drug product. Responsibilities include characterization of molecular identity, purity, aggregation status, charge isoforms, potency, and stability of monoclonal antibody-based product using HPLC (including SEC, RP-HPLC, IEX, HIC, affinity etc), electrophoresis (including SDS-PAGE, Western blotting, IEF, and capillary electrophoresis C-SDS and C-IEF), ELISA, FRET, qPCR and other microtiter plate-based methods, and non-labeling binding assays (Octet, Biacore, etc); participation in purification of monoclonal antibodies from cell culture harvest or other protein purification process for product characterization; participation in characterization of monoclonal antibody and other protein-based product by peptide mapping and LC-MS; interaction with R&D, QC and Manufacturing groups and presentation of data in group settings.

Education: A BS/MS degree in a scientific discipline plus minimum 4/2 years of relevant experience (preferably in monoclonal antibody analytical development).

Experience: HPLC, Antibody, Protein

Sr. Research Associate

Description:

This position will participate in the development of analytical methods to support the CMC characterization and comparability studies of preclinical to clinical monoclonal antibody drug substance and drug product. Responsibilities include analytical development of MS- and LC-MS based methods for characterization of novel monoclonal antibodies and other protein based product at preclinical and clinical studies; performing MS analysis of intact molecule, isoforms, and fragments generated by various enzyme digestion; peptide mapping analysis for monoclonal antibody sequence and subunit analysis, glycosylation analysis and isoform quantitation by LC-MS; participating in method development for identity, purity, aggregation status, charge isoforms, potency, and stability of monoclonal antibody-based product using HPLC (including SEC, RP-HPLC, IEX, HIC, affinity etc), electrophoresis (including SDS-PAGE, Western blotting, IEF, and capillary electrophoresis C-SDS and C-IEF), and other protein chemistry tools; interaction with R&D, QC and Manufacturing groups and presentation of data in group settings.

Education: A BS/MS degree in a scientific discipline plus minimum 5/3 years of relevant experience in monoclonal antibody or protein-based product characterization by LC-MS, enzymatic digestion, and sample preparation.

Experience: Mass spectrometry

Sr. Scientist, Cell Culture & Process Development

Description:

This position will be responsible for cell culture and upstream process development for multiple monoclonal antibody products intended for preclinical and Phase I clinical studies. Responsibilities will include development of high performance cell culture process from stable pool or selected research cell bank (RCB) of engineered CHO cells in shake flasks and bench-top bioreactors; generation of high titer monoclonal antibodies secreted culture media harvest; purification of multi-gram quantity of mAb for preclinical studies and reference materials; participation in preclinical to Phase I process and product comparability studies; support of CMC process control with project teams and CMO’s.

Requirements:

  • PhD with a minimum of 5 years of experience developing mammalian cell culture process development for protein preferably monoclonal antibody expression;
  • Experiences in cell culture process scale up, scale down, characterization and transfer are required;
  • Demonstrated success in technical proficiency, bioreactor operation, timely delivery of multi-gram quantity of mAb for preclinical studies and reference material use;
  • Understanding data acquisition and process control, and data management is also required, experience in a cGMP production environment is a plus;
  • Other requirements include knowledge and experience in statistics and DOE, interpersonal and organizational skills, oral and written communication skills, ability of multi-tasking effectively and operate both independently and in team settings

Sr. Scientist, Assay Development

Description:

This position will be responsible for assay development in support of CMC/ IND submission of multiple monoclonal antibody-based products. Responsibilities will include development, qualification and transfer of potency assays for characterization, QC release and stability testing of monoclonal antibody drug substance and drug product; non-cell based assay development and implementation to assess antibody-antigen or target binding and ligand blocking activities; cell-based assay development to evaluate Fc effector function activities of mAb including ADCC, CDC and ADP; Support drug substance and drug product formulation development and batch comparison studies with potency assays; Interpret, present and deliver data to appropriate stakeholders; author and review technical reports and sections of regulatory filing; interact with discovery and other development groups on a scientific and strategic level. Assay format should include but not limit to antigen/ cell receptor binding assay by non-labeling BLI (Octet) or SPR (Biacore), labeling ELISA or Luminex assays, FRET, and other plate-, colorimetric- or fluorescence-based assays, cell-based assays, FACS, SDS-PAGE, Western blotting , etc.

Requirements:

  • PhD plus Minimum 5 years of experience developing potency assays used for CMC support in the biotechnology or pharmaceutical industry;
  • Background in immunology, cell biology, protein chemistry or cancer drug development;
  • Experience working in a GMP regulatory environment desirable;
  • Other requirements include knowledge and experience in statistics and DOE, interpersonal and organizational skills, oral and written communication skills, ability of multi-tasking effectively and operate both independently and in team settings

Patent Agent/Technology Specialist

Description:

Agenus is seeking a highly qualified Patent Agent or Technology Specialist with 2 years of experience in biotech patent prosecution and/or diligence preferred. The candidate must be curious, smart, and hard-working, and have good judgment, high integrity, and superior writing and communication skills.

Responsibilities include:

  • Assistance in cross-departmental diligence review of acquisition and in-licensing opportunities, including working with business development colleagues to develop and maintain relationships with third parties
  • Assistance with freedom-to-operate, invalidity, and non-infringement analyses of third party patents and applications and other competitive intelligence activities
  • Database searches and review and analysis of patent and technical literature
  • Contribution to patent prosecution and other intellectual property matters on an as-needed basis
  • Clear and effective communication with internal and external stakeholders
  • Other administrative, legal, and corporate duties as required

Key qualifications:

  • Ph.D. in immunology or related field, with 2 years of experience in biotech patent prosecution and/or diligence preferred
  • Registration to practice before the U.S. Patent and Trademark Office preferred
  • Proven ability to analyze and evaluate technical documents and inventions and to conduct database searches
  • Effective time management skills
  • Team-oriented approach
  • Curious, smart, and hard-working
  • Good judgment, high integrity, and superior writing and communication skills